A Midcourse Assessment of Hantavirus Pulmonary Syndrome

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A midcourse assessment of hantavirus pulmonary syndrome.

Our understanding of infectious diseases follows a natural course—the initial discovery of the cause, the exploration of the natural history and biology of the etiologic agent, and finally the cure or solution. The discovery of Sin Nombre virus (SNV), one of the viruses causing hantavirus pulmonary syndrome (HPS), is unparalleled in terms of the rapid progress of the scientific investigation le...

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Hantavirus pulmonary syndrome.

Hantavirus pulmonary syndrome (HPS) is a severe disease characterized by a rapid onset of pulmonary edema followed by respiratory failure and cardiogenic shock. The HPS associated viruses are members of the genus Hantavirus, family Bunyaviridae. Hantaviruses have a worldwide distribution and are broadly split into the New World hantaviruses, which includes those causing HPS, and the Old World h...

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Hantavirus pulmonary syndrome.

Hantavirus pulmonary syndrome, also known as hantavirus cardiopulmonary syndrome, is a recently described infectious syndrome found throughout the Americas. Although infection is sporadic and uncommon compared with other atypical pneumonia syndromes, its high mortality rate warrants the maintenance of a high index of suspicion in rural settings. Because no specific therapies are available for t...

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Hantavirus pulmonary syndrome.

An outbreak of Hantavirus Pulmonary Syndrome (HPS) occurred in the western U.S. in 1993. This outbreak was surprising because serious disease due to hantavirus had not been reported previously in the U.S., and hantavirus had not been documented to cause significant pulmonary disease. Epidemiologic investigation discovered a novel strain of hantavirus as the etiologic agent of HPS. The Centers f...

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Treatment of hantavirus pulmonary syndrome.

Viruses in the genus Hantavirus can cause one of two serious illnesses when transmitted from rodents to humans: hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). Of the two diseases, HPS is more severe with an approximate 40% mortality across the Americas. The high rate of mortality could be reduced if effective therapeutics could be discovered for treatment o...

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 1999

ISSN: 1080-6040,1080-6059

DOI: 10.3201/eid0501.990124